Development of knowledge about the structure of DNA

By Beth_274

  • Mendel

    Mendel
    Gregor Mendel was also know as the "father of genetics." Mendel discovered the fundamental laws of inheritance and that genes come in pairs are inherited as distinct units, one from each parent. Mendel found the Law of Segregation, The Law of Independent Assortment, and The law of Dominace. Mendel's pea plants experiments took eight years (1856-1863) and he published the results in 1865.

  • Miescher

    Miescher
    Friedrich Miescher first discovered DNA in 1870 by collecting white blood cells from pus and studied the nuclei of white blood cells. He also discovered and named this chemical substance that was rich in nitrogen and phosphorus atoms, Nuclein. This name progressed over time is now know as deoxyribonucleic acid. He identified DNA as part of a chromosome in 1871.

  • Sutton and Boveri

    Sutton and Boveri
    provided the first conclusive evidence that chromosomes carry the units of inheritance and occur in distinct pairs.

  • Pauling

    Pauling
    Pauling discovered that a helix is the structure of a class of proteins. They also discovered the Beta Strand which is different polypeptide chains that run along side each other and linked together by hydrogen bonds which consist of 5-10 amino acids. Linus received The Nobel Peace Prize in Chemistry 1954 for his research into the nature of the chemical bond and its application to the elucidation of the structure of complex substances.

  • Morgan

    Morgan
    American zoologist and geneticist, famous for his experimental research with the fruit fly (Drosophila) by which he established the chromosome theory of heredity. He also discovered that there were sex chromosomes and that there were linked genes. For his discoveries concerning the role played by the chromosome in heredity, he was awarded the Nobel Prize in 1933.

  • Franklin and Wilkins

    Franklin and Wilkins
    Rosalind Franklin was an English chemist and X-ray crystallographer who was studying the structure of DNA using x-ray diffusion. Franklin diffracted the helical shape of DNA using uniformly oriented strands created by Maurice Wilkins. She also provided measurements of DNA while Wilkins provided the samples.

  • Levene

    Levene
    discovered 2-deoxyribose (a sugar derived from d-ribose by removing an oxygen atom), which is part of the deoxyribonucleic acid (DNA) molecule.

  • Chargaff

    Chargaff
    discovered that the bases pairs Adenine and Thymine pair as well as Guanine with Cytosine. Through careful experimenting, Chargaff discovered two rules that helped lead to the discovery of the double helix structure of DNA. Chargaff's rule is that the amount of cytosine is approximately the same amount as guanine.

  • Watson and Crick

    Watson and Crick
    Watson and Crick were building 3-D models of DNA out of cardboard and wire but were incorrect until they saw Franklin's x-ray patterns. After seeing her information, Watson and Crick made the first correct 3-D model of DNA and received The Nobel Prize in Physiology or Medicine 1962 for their discoveries concerning the molecular structure of nucleic acids and its significance for information transfer in living material