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Period: to
DNA timeline
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Gregor Mendel
tested 5,000 pea plants. He put in two generations which are now known as mendel's Principles of Heredity or Mendelian inheritance. He worked with seven different characteristics. plant height, pod shape and color, seed shape and color, and flower position and color. He showed that when a yellow and green peas were mixed they always ended up yellow. -
Charles Darwin
He discovered natural selection. This is a difference in survival and reproduction of people because of a difference in phenotype. -
Frederick Miescher
He isolated Dna from cells for the first time. He called this nuclein. He first identified Dna as a distinct molecule. -
Walther Flemming
He described what chromosomes did during animal cell division.
He would stain chromosomes to observe them and describe the process of mitosis. -
Archibald Garrod
He pioneered the field of inborn errors of metabolism. He discovered alkaptonuria to understand inheritance. -
Wilhelm Johannsen
He created the word "Gene" to describe the Mendilian unit of heredity. He also used the words genotype and phenotype to seperate the genetis traits of someone form their outer appearence. -
Thomas Hunt
won nobel prize for describing the role that chromosomes play in heredity. He studied fruit fly chromosomes which showed that chromosoems carry genes. -
Hermann muller
He showed that X-rays can cause mutations. -
Beadle and Tatum
Their experiments proved Archibald Garrods theory that heredity diseases are "inborn errors of metabolism" . They did experiment using neurospora crassared bread mold -
Oswald Avery
Worked on the mystery of Inheritince. Techniques were available to remove various organic compounds from bacteria. Retired but he decided to continued work for five years. S-Strain baceria was treated with protease enzymes and removed the proteins from the cells. The rest was placed with the R-Strian. Then treated with deoxyribonuclease enzyme which removed the dna. -
William Astbury
He obtained the first X-ray diffraction pattern of dna. That revealed that dna must have a regular periodic structure. -
Rosalind Franklin
She worked on the X-ray diffraction images of DNA and led to the discovery of Dna. She led pioneering work on molecular structures of viruses. -
Erwin Chargaff
He found two rules that lead to the discovery of the double helix structure of dna. The first rule is the number of Guannine units equals the number of cytosine units. The second rule is the amounts of guanine, cytosine, adenine and thymine bases are different from one species to the next. -
Hershey and chase expiriments
series of expiriments conducted hat helped to confirm that DNA is genetic material. scientists still thought thay proteins carried information for inheritance because Dna appeared simpler that proteins. They showed that when bacteriophages infect infect bacteria the dna enters the host bacterial cell. -
Francis Crick
Also a co-discoverer of the structure of dna. He was very important to revealing the genetic code.Frederick Miescher -
Herbert Boyer
produced the first human proteinin a bacterium, marketed the
first recombinant DNA drug, human insulin. -
Patrick Brown
wanted to compare the DNA of whole organisms. This gave infornation in variation in genetic expression and development that cannot be obtained with individual sequence comparisons. -
James Watson
He was a co-discoverer of the structure of dna. He wrote a book on dna structure. He was in charge of the human Genome project. -
Steve Fodor
He was put in charge of developing a process to generate miniature high-density arrays of biological compounds. It led to the first DNA Genechip. Founder of Affymetrix which produces DNA microarrays to look over gene expression and genetic variations. -
John Sulston
He understood and explained the dividing of cells. He completed the "working draft" of the human genome sequence. -
John Ventor
He began the journey to sequence the human genome. He developed the EST method of finding genes. -
Frank Griffth
He proved that dna is a molecule of inheritance. first experiment suggesting that bacteria are capable of transferring genetic information through a process known as transformation.
